Forecasting Ecological Genomics: High-Tech Animal Instrumentation Meets High-Throughput Sequencing

Forecasting Ecological Genomics: High-Tech Animal Instrumentation Meets High-Throughput Sequencing.

Recent advancements in animal tracking technology and high-throughput sequencing are rapidly changing the questions and scope of research in the biological sciences. The integration of genomic data with high-tech animal instrumentation comes as a natural progression of traditional work in ecological genetics, and we provide a framework for linking the separate data streams from these technologi...

Once again high tech meets low tech on chromosome 6.

1 are to be congratulated on their research of the autosomal dominant Stargardt disease gene (STGD3). This study contains some extremely complex issues that require some clarification , as well as some basic and simple findings that should be emphasized. The basic issues center on gene-alogy, phenotype classification (lumping vs splitting), genotype and haplotype analysis, and statistics. Since...

A radiation oncologist's story: high tech meets high touch.

I grew up hearing stories about my grandmother, a missionary and an American-trained surgeon, who brought her doctoring skills to Korea at the turn of the twentieth century. She spent her first few months there learning the language and customs of this ancient kingdom where she’d spend the rest of her life. Working in a preantibiotic era, supportive care was an important part of her practice. K...

High-throughput sequencing technologies.

The human genome sequence has profoundly altered our understanding of biology, human diversity, and disease. The path from the first draft sequence to our nascent era of personal genomes and genomic medicine has been made possible only because of the extraordinary advancements in DNA sequencing technologies over the past 10 years. Here, we discuss commonly used high-throughput sequencing platfo...

SnapShot: High-Throughput Sequencing Applications